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Indeed, in Hgf- or Met-null mice, the development of liver is severely impaired and the placental labyrinth is hypomorphic, leading to death in utero ( MET activation is involved in angiogenesis, wound healing, cell scattering, proliferation, and cancer invasion ( In this review, we focus on the genetic, molecular, and cellular mechanisms driven by HGF-MET in the nervous system, starting from their involvement in brain development and ending to their implication in neurodevelopmental disorders (NDDs)

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