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There is benefit in the inferior caval vein occlusion (Vukojevic et al., 2018
Li N, Tan S, Wang Y, Deng J, Wang N, Zhu S, et al
These effects are typically most pronounced during dose escalation and often diminish with continued use, though some patients experience persistent symptoms requiring dose adjustment or discontinuation
This "waste" means you may be taking a high dose on paper, but your cells are only receiving a tiny fraction of it
Diabetologia 53(12):24802486
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