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This imbalance is hypothesized to contribute to dysfunctions in the reward system, potentially manifesting as anhedonia and other depressive symptoms 45 , a clinical observation that aligns with the psychiatric side effects noted in GLP-1 RAs therapy
Diabetes 54 , 32583264 (2005)
It keeps weight loss steady and sustainable
6 studies scored three points, and the remaining 4 scored five points, indicating medium and high-quality studies, respectively
The data indicate that upregulation of adiponectin expression is a mechanism underlying exendin-4 and GLP-1Rs role in regulating insulin sensitivity
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