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Metallothioneins (MTs) MTs are highly conserved, low-molecular-weight, cysteine-rich non-inducible enzymatic proteins that participate in metabolism of essential metals, their detoxification, and scavenging of oxyradicals (Sigel et al
These may be a consequent result of type 2 diabetes condition associated with the buildup of glucose in the bloodstream
Suspected adverse reactions should be reported via the MHRA Yellow Card Scheme (yellowcard.mhra.gov.uk)
249 Furthermore, 5-FU/cisplatininduced interferon responses upregulate ADAR1 via JAK/STAT, promoting A-to-I RNA editing that stabilizes SCD1 mRNA, reprograms lipid metabolism, activates Wnt/-catenin signaling, and sustains stemness and chemoresistance in gastric cancer
