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8.6 Ferroptosis affects depression by regulating gut flora The brain-gut axis is a bidirectional communication network that connects cognitive and emotional functions of the brain to gut activity through neural pathways, neuroendocrine and neuroimmune systems, and gut microbiota (Mayer et al., 2022)
It slows gastric emptying, reduces hunger signals to the brain and stimulates insulin release when blood glucose is elevated, helping people with type 2 diabetes or obesity improve glycemic control and often reduce body weight
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