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The therapeutic utility of native GLP-1 is limited by its rapid degradation [2], primarily mediated by dipeptidyl peptidase-4 (DPP-4) and secondarily by neutral endopeptidases (NEPs) and renal clearance [3, 4]
The primers used in this study are listed in Supplementary Table S1
If you are already familiar with medications like Ozempic, you may notice some similarities in how your body responds initially
The goal is to find a sustainable dose that respects your biology, not to become a kitchen chemist with unsafe compounded vials
The dose adjusts when data justifies it
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