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Upon catalysis of COXs, dihomo--linolenic acid (DGLA) and arachidonic acid (AA) can be oxidized by radical-mediated lipid peroxidation and produce prostaglandins, which linking the lipid peroxidation directly to inflammation and apoptotic processes [32,33,34]
Unlike older weight loss medications, tirzepatide's mechanism targets two distinct hunger-signaling pathways, which is why starting low and titrating gradually helps your body adapt
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