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Liraglutide, in combination with metformin, has demonstrated synergistic antipancreatic cancer effects in both in vivo and in vitro studies [8]

This process involves a breakdown of the cell membrane, leading to cell swelling, rupture of organelles, and the spilling of cellular contents into the surrounding space, which in turn sparks an inflammatory response in nearby tissues

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Aib: -aminoisobutyric acid ApoB: apolipoprotein B CKD: chronic kidney disease FDA: Food and Drug Administration GI: gastrointestinal GLP-1 RA: glucagon-like peptide-1 receptor agonist HCC: hepatocellular carcinoma LDL-C: low-density lipoprotein cholesterol MASH: metabolic dysfunction-associated steatohepatitis MRI-PDFF: magnetic resonance imaging-proton density fat fraction NAFLD: nonalcoholic fatty liver disease NASH: nonalcoholic steatohepatitis T2DM: type 2 diabetes mellitus THR-: thyroid hormone receptor- This comparative perspective provides a summary of current evidence and should not be misconstrued as medical advice