While this study was not a head-to-head clinical trial comparison, it may be relevant that at week 12 of a weekly dosing regimen, some studies suggest that participants treated with semaglutide (Wegovy, Novo Nordisk) had an approximately 6% decrease from baseline in body weight, whereas those treated with tirzepatide (Zepbound, Eli Lilly) had an approximately 8% decrease from baseline in body weight at the same time period, Bays said
Edited by: Bruguera-Cortada M, Mino-Fugarolas G, Pons-Romero F, Moreno-Otero R
Mitochondrial stress may increase free-radical production, while oxidative damage may further impair the electron transport chain
The authors noted that this reduction in HbA1c was likely to reflect a clinically meaningful effect, as an HbA1c of 7% is the treatment goal of the American Diabetes Association (Axelsson et al., 2017)
But as important as neutralizing reactive oxygen species like free radicals, aiding detoxification, staving off oxidative damage, and regenerating other antioxidants are, they aren't the only functions glutathione has