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In NOD mice, it delayed T1D onset, reduced insulitis, inhibited the expansion of T-BET+ CTLs, and promoted a T cell exhausted signature in the spleen and pancreatic lymph nodes (122, 123)
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In addition, long-term TB treatment studies in mice, evaluating the effects of aspirin in combination with pyrazinamide and other TB drugs are needed to determine the potential role of aspirin in reducing TB treatment and preventing relapse
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High Dose (10 mcg/kg): Typically reserved for acute/severe injuries or advanced orthopedic conditions
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