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Take home message Retatrutide is the most effective weight-loss medication tested so far, with 28.7% body-weight loss reported at the highest dose in TRIUMPH-4
There are also people who should not use GLP-1 medications
Abstract Glucagon-like peptide-1 receptor agonists (GLP-1RAs) have a reliable hypoglycaemic and weight-loss effect that can intervene in obesity, which is the basis of type 2 diabetes pathology
The optimization phase provides plenty of opportunity to accelerate fat loss once side effects stabilize
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