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While these studies have raised questions, a 2024 multinational cohort study of 145,000 patients found no significant increase in thyroid cancer risk (HR 1.19, 95% CI 0.931.52) over 3.9 years compared to dipeptidyl peptidase-4 (DPP-4) inhibitors

potential worsening of diabetic retinopathy in people with type 2 diabetes using semaglutide

GLP-1 receptor agonists have been associated with an increased risk of gallstone formation in some patients

Higher concentrations (3-4%+) are for experienced users who have established tolerance

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