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Cycle Guidelines Tesamorelin Cycle Guidelines Approach Standard Duration 26 weeks Review Point Week 26 imaging Best For Phase III trial exposure pattern Approach Extended Duration 52 weeks Review Point Week 52 imaging Best For Pooled Phase III extension data Approach Long-term (NAFLD context) Duration 12 months Review Point 12-month imaging Best For Liver-fat study exposure pattern Trial data showed visceral fat returns toward baseline after stopping