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Ethics Statement The experiments reported in this manuscript were conducted according to the guidelines stated in the Principles of Laboratory Animal Care (Institute for Laboratory Animal Research., 2011) and the Norma Oficial Mexicana de la Secretara de Agricultura, Ganadera, Desarrollo Rural, Pesca y Alimentacin (SAGARPA, Mxico) Especificaciones tcnicas para la produccin, Cuidado y uso de los animales de laboratorio (Agricultura y Ganadera, 2001)