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Acute Kidney Injury Due to Volume Depletion: There have been postmarketing reports of acute kidney injury, in some cases requiring hemodialysis, in patients treated with GLP-1 receptor agonists
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However, the Food and Drug Administration (FDA) guidelines do not require the assessment of muscle quality or volume in clinical trials assessing the efficacy of GLP-1 drugs for weight loss
CRC Press, Boca Raton, pp 77104 Barroso JB, Corpa FJ, Carreras A, Rodriguez-Serrano M, Esteban FJ, Fernandez-Ocana A, Chaki M, Romero-Puertas MC, Valderrama R, Sandalio LM, del Rio LA (2006) Localization of S -nitrosoglutathione and expression of S -nitrosoglutathione reductase in pea plants under cadmium stress
This cascade leads to neuronal apoptosis and energy deficits, particularly in the prefrontal cortex and hippocampus (Leong et al., 2020)
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