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IGF1 stimulates crypt expansion via differential activation of 2 intestinal stem cell populations

Competing interest The authors declare that they have no competing interests

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215 Findings from clinical trials using cytokine inhibitors have not been consistently positive, but a growing body of evidence suggests there may be a subset of depression patients with elevated inflammatory cytokine levels, such as those with co-occurring autoimmune or other inflammatory conditions, who are likely to benefit from the addition of cytokine-blocking agents to their treatment regimen