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It was clinically approved by both the Food and Drug Administration (FDA) and the European Medicine Agency (EMA) in 2014 for the treatment of relapsing-remitting multiple sclerosis (MS), showing a significant efficacy over 2 years versus placebo and a favorable benefit-risk profile in two phase-III clinical trials, although with several adverse effects such as nausea, diarrhea, abdominal pain and leukopenia in some patients [282, 283]
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However, their safety and efficacy in pregnancy require more research to determine optimal use in fertility treatments and assisted reproduction technologies (ART)
CA: A Cancer Journal for Clinicians
7 Days Swelling, tenderness, and bruising from fat dissolving injections are common and can last up to 7 days as the body begins to process the treated fat cells
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