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Finally, in a two-month randomized, double-blind, placebo-controlled study in 40 individuals with type 2 diabetic nephropathy (kidney disease), daily curcumin ingestion (66.3 mg) significantly reduced urinary concentrations of proteins and inflammation markers (TGF-, IL-8), suggesting that curcumin might be helpful with slowing the progression of kidney damage and preventing kidney failure (74)

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History of hormone-sensitive conditions As a precaution, until more human data is available