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However, in the posterior cortex, CAT activity was reduced in the VPA+LipRSV group compared to the VPA group, indicating that LipRSV treatment may have negatively modulated the enzymes expression or activity, either by attenuating oxidative stress and thus reducing enzymatic defense needs, or through a possible pro-oxidant effect dependent on the region and experimental conditions
SCD1 catalyzes the desaturation of palmitic acid (16:0) into palmitoleic acid (16:1) and stearic acid (18:0) into oleic acid (18:1) 48
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Single biopsies often fail to reflect the full spectrum of resistant subclones across metastatic sites and treatment stages
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