does glp 1 wear off When you’ve been on a GLP-1 for some time, it can feel like it’s wearing by Day 5 or 6, which can create stress, different eating habits, and frustration when meals don’t look the same., This How to Wean Off GLP-1

The Clothing Test: You will likely notice your clothes fitting differently before you see a massive change in your face or limbs, as visceral fat (the fat around organs) often begins to mobilize first

Friesen C, Kiess Y, Debatin KM

Bruising is the most common complaint

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Trials suggest its side effect profile looks a lot like whats been seen with other GLP-1 drugs like Wegovy and Zepbound