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TRIUMPH-3: Obesity with Established Cardiovascular Disease (July 2026) TRIUMPH-3 enrolled 1,949 adults with severe obesity (BMI 35) and established cardiovascular disease, with or without type 2 diabetes, randomized 1:1:2 to retatrutide 9mg, 12mg, or placebo over 80 weeks
Santos LB, Mizubuti GB, da Silva LM, Silveira SQ, Nersessian RSF, Abib AdCV, Bellicieri FN, Lima Hdo, Ho AMH, dos Anjos GS, de Moura DTH, de Moura EGH, Vieira JE
Mzm1 influences a labile pool of mitochondrial zinc important for respiratory function
