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Effect of insulin glargine up-titration vs insulin degludec/Liraglutide on glycated hemoglobin levels in patients with uncontrolled type 2 diabetes: the DUAL V randomized clinical trial

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For patients with established cardiovascular disease, baseline lipids also inform the overall risk-benefit calculation for GLP-1 therapy, which has demonstrated cardiovascular outcome benefits in high-risk populations

It has also received related adverse-event reports