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Many substances that promote healing share molecular pathways with cancer growth

During chronic kidney disease (CKD), the AMPK signaling pathway is inhibited, which result in mitochondrial biogenesis (nuclear respiratory factor 1 and mitochondrial transcription factor A) as well as mitochondrial-specific proteins (cytochrome C and mitochondrial complex IV) downregulated, leading to M1 polarization of macrophages (101)

These references make clear that B12 therapy is primarily about treating deficiency, not directly burning fat

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