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Vitamin B12 can help combat and prevent a wide range of diseases

Their real advantage over fad diets and over-the-counter fat burners is honest: predictable nutrient dosing, documented physiologic roles, and administration under medical supervision

[12] Gastric acid-suppressing agents (proton-pump inhibitors and H-receptor antagonists) diminish dietary B12 liberation from protein complexes, a pharmacodynamic interaction that can exacerbate underlying deficiency

Alternatively, 1000mcg can be given daily SC/IM for 2-7 days, followed by maintenance treatment

Patients who have been on stimulants in the past often require a higher phentermine dose to achieve meaningful appetite suppression, and in some cases outcomes are more limited