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[1] [2] When treatment is interrupted for extended periods, the body may lose its adaptation to the medication, and restarting at a full maintenance dose could increase the risk of gastrointestinal symptoms

Metabolic flux analysis utilizing 13 C labeled glutathione would yield additional information regarding flux of glutathione and glutamate under various conditions

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Summary Keywords glucagon-like peptides, intestine, incretins, metabolism, glucose-dependent insulinotropic polypeptide Citation Morrow NM, Hanson AA and Mulvihill EE (2021) Distinct Identity of GLP-1R, GLP-2R, and GIPR Expressing Cells and Signaling Circuits Within the Gastrointestinal Tract