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Concomitant medications in cases of GLP-1 RA-related NAEs mirrored patterns observed in all NAE cases, with frequent co-administration of oral antidiabetics and insulin (Fig
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Earlier animal studies with malnourished mothers reported that delayed ossification is associated with decreased maternal body weight, and maternal malnutrition or reduced intake are common pathways to decreased fetal weight/growth and ossification (6669), but malnutrition models did not report the increase in major congenital anomalies reported after gestational exposure to GLP-1 agonists
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