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With intramuscular (IM) injections the standard treatment for severe deficiency or malabsorption conditions like pernicious anaemiaserum B12 levels rise rapidly, typically reaching therapeutic ranges within 2448 hours after the first injection

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This selectivity represents a fundamental difference from not only full-length growth hormone but also growth hormone secretagogues and analogs like tesamorelin, which increase endogenous growth hormone and subsequently elevate IGF-1

B12 acts as a cofactor for two important enzymes: methionine synthase, which is involved in DNA production and methylation processes, and methylmalonyl-CoA mutase, which is essential for fatty acid metabolism and energy production

The lyophilized format supports storage stability, laboratory handling, and long-term preservation under appropriate conditions