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Originally developed for diabetes management, it has gained recognition for its powerful weight-loss benefits

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Constipation: common but manageable Constipation is frequently reported with GLP-1 therapy and may worsen with: Low fibre intake Reduced food intake Inadequate hydration A sedentary lifestyle Helpful measures may include: Adequate water intake Fibre-rich fruits and vegetables Walking or light physical activity Isabgol or fibre supplementation if medically appropriate To reduce nausea, many patients find relief by switching to lighter regional Indian meals and smaller portions during the first few weeks

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Many patients with thyroid conditions, particularly hypothyroidism, struggle with weight management, making weight-loss medications like Wegovy potentially beneficial

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Non-GLP-1RA users (unexposed) were individuals with no record of GLP-1RA prescriptions before the index date

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doi: 10.1042/CS20171459 166 TessaroFHGAyalaTSMartinsJO

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