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(Regulatory Toxicology and Pharmacology, 2020) reported a preclinical safety package designed to support potential drug development
1) Shock: Shock can appears, so fully observe, and when abnormality has found, stop injecting and operate proper action
In most cases, its acceptable
Hydroxocobalamin injection does not need glutathione to detoxify it because it can easily be converted to both active forms of B12 and does not contain a toxic donor, cyanide
Its important to adjust treatment plans for these cases
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