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Lab review before starting: A baseline IGF-1, fasting glucose, and (where indicated) a thyroid panel sets the framework for response tracking

Tirzepatide Lys 16 may have a stacking interaction with GIPR Phe 127

J Neurosci2001 May 15;21(10):3639-45

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It's worth noting that the impact on blood sugar control is generally less pronounced than missing doses of shorter-acting medications like insulin or sulphonylureas, due to semaglutide's extended half-life