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Should the SELECT Trial make us comfortable using GLP-1 receptor agonists in HFrEF
Heres the problem: Inconsistent quality
The b12 shots did not hurt at all and I hate shots
Like where do you think it becomes like, okay, this is an appropriate drug for you say its somebody who maybe on one end is saying, I just want to lose 15, 20 pounds, I exercise, I think I eat pretty, pretty healthy, not overeating, but I just cant drop the pounds
however, of those who showed glycemic control, there was a significantly lower incidence of hepatic encephalopathy.33 These two studies demonstrate that satisfactory glycemic control in cirrhotic patients can be achieved in only one third of cases by using current therapeutic schemes possibly because of hepatotoxicity, hypoglycemia and lactic acidosis, as most of antidiabetic drugs are metabolized in the liver.38 The recommendations of changes in diet and exercise regimens are empirical, as these measures have not been evaluated in patients with hepatic insufficiency
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