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The 15-residue fragment now referred to as BPC-157 corresponds to a partial sequence of that parent compound and is produced by solid-phase peptide synthesis rather than extracted from biological material
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TB-500: The Synthetic Healer TB-500 is a synthetic version of thymosin beta-4, a naturally occurring protein that promotes healing and regeneration
The molecule was developed by Frank Ng's group at Monash University and Metabolic Pharmaceuticals in Australia during the 1990s and 2000s as a potential anti-obesity drug intended to isolate the lipolytic region of hGH without activating the growth hormone receptor or raising IGF-1.nnIn published preclinical work, the fragment has been shown to stimulate lipolysis, suppress lipogenesis, and modulate the beta-3 adrenergic receptor pathway in adipose tissue rather than acting through the classical hGH receptor
One finding that gets a lot of attention: BPC-157 appears to reverse NSAID-induced gut damage in animal models
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