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Protein aliquots (30 g) were separated in 12% polyacrylamide gels using the Mini-PROTEAN III apparatus (Bio-Rad, USA)
They represent a new therapeutic approach able to act directly on the heart or kidneys, independently of insulin sensitivity (Lopaschuk and Verma, 2020
The STEP 1 trial (Wilding et al., The Lancet, 2021) showed an average weight loss of 14.9% over 68 weeks versus 2.4% in the placebo group a landmark result that established semaglutide as the benchmark for GLP-1 weight loss
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