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ERdj5 is required as a disulfide reductase for degradation of misfolded proteins in the ER
doi: 10.1177/0333102410378358 86
M2 macrophages exhibit angiogenic and proinvasive properties, producing growth factors, chemokines, and MMPs that stimulate tumor growth, invasion, and metastasis (93), particularly facilitating tumor cell extravasation and growth in secondary sites
As mentioned, these side effects are due to food staying in the stomach longer as a result of delayed digestion and gastric emptying
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