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We demonstrate here that metabolism by intestinal microbiota of dietary l-carnitine, a trimethylamine abundant in red meat, also produces TMAO and accelerates atherosclerosis in mice
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In summary, although most studies of "subjective" symptoms suggest a beneficial effect of L-carnitine supplementation for maintenance dialysis patients, the Work Group concluded that the heterogeneity of study design, and the difficulty in measuring these and related symptoms in an unbiased manner render the available evidence in this area inconclusive
