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Glutathione and thioredoxin redox during differentiation in human colon epithelial (Caco-2) cells

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however, excessive intake can lead to severe hepatotoxicity, which may result in acute liver failure ( Glutathione peroxidase 4 (GPX4) is a selenoprotein essential for cellular defense against oxidative stress, with a specific function in reducing lipid peroxides and maintaining redox homeostasis ( The search for effective agents to alleviate ER stress and oxidative damage in ALI has recently garnered attention ( The present study investigates the hepatoprotective effects of TA against APAP-induced liver injury in mice, focusing on its regulation of oxidative stress and ER stress pathways