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Topical delivery applies the compound directly to the area being treated, so patients can focus on skin firmness, texture, scalp support, or hair wellness without turning to risky online sources

Boston, MA Frequently asked questions In the SURMOUNT-1 trial published in The New England Journal of Medicine (Jastreboff et al., 2022), participants on weekly tirzepatide 15 mg lost an average of 20.9% of body weight at 72 weeks versus 3.1% on placebo

Today's announcement by the FDA substantiates those concerns

Promotes overall skin vitality and long-term skin health

Updated result (January 26, 2026): Roche announced full 48-week Phase II results from the CT388-103 trial (NCT06525935, n=469)