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In March 2026, Structure reported 44-week topline data from the ACCESS II Phase 2 study, showing placebo-adjusted weight loss of up to 16.3%, which the company described as the highest efficacy demonstrated among oral GLP-1 receptor agonists at that time point

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To compare continuous variables among groups, Students t test, Mann-Whitney U test and Friedman test were utilized

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87 The importance of being aware of your risk profile as it relates to established, modifiable risk factors cannot be overstated