Most common side effects are gastrointestinal: nausea, vomiting, diarrhoea, constipation, and abdominal discomfort
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Or look at Tesofensine, which works centrally in the brain by inhibiting the reuptake of neurotransmitters like dopamine, serotonin, and noradrenaline, thereby influencing appetite and energy expenditure
doi: 10.2337/dc23-S009 10 KelseyMDNelsonAJGreenJBGrangerCBPetersonEDMcGuireDKet al
Introduction As living standards rise, the convergence of excessive caloric intake, declining physical activity, and population ageing is driving a sharp increase in diabetes mellitus in China, and T2DM now accounts for 9095% of all cases [1]