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It is used in combination with GLP-1 in the weight-loss medications Zepbound (US) and Mounjaro (UK) - known as dual GIP/GLP-1 receptor agonists
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The FDA-approved prescribing information emphasizes that unopened pens should remain refrigerated until the expiration date printed on the label
Contrave (Naltrexone/Bupropion) Contrave is an FDA-approved once-daily oral prescription medication that combines naltrexone and bupropion to reduce hunger and food cravings by targeting reward pathways in the brain
doi: 10.1136/bmj.d7771 29 GersteinHCColhounHMDagenaisGRDiazRLakshmananMPaisPet al
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