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BPC 157 was given per-orally, in drinking water (10 g/kg or 10 ng/kg, 0.16 g/ml, or 0.16 ng/ml 12 ml/rat/day) till sacrifice, or alternatively, 10 g/kg and 10 ng/kg intraperitoneally once daily
Animal studies have shown a significant reduction in postoperative complications, particularly anastomotic dehiscence
Research Note: Published preclinical research, including a 2025 literature and patent review in the journal Pharmaceuticals (Jzwiak et al., 2025, Pharmaceuticals ), has documented BPC-157's effects on angiogenesis, nitric oxide signaling, and tissue protection in animal models, though authors note that no completed human clinical trials have been published to confirm these effects in people
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