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Side effects for GLP-1s may include nausea, vomiting, stomach pain, upset stomach, dizziness, constipation, feeling bloated, belching, gas, headaches, and fatigue
In the UK, NICE recommends GLP-1 receptor agonists as second- or third-line treatment options for type 2 diabetes when metformin and other oral agents have not achieved adequate control (NICE NG28)
High-Risk Patient Profiles Using for Off-Label Weight Loss (No Diabetes) The July 2024 study found 7x higher NAION risk in patients taking semaglutide for weight loss versus diabetes
doi:10.1080/07315724.2019.1661804
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