PTEN and NF1 inactivation in Schwann cells produces a severe phenotype in the peripheral nervous system that promotes the development and malignant progression of peripheral nerve sheath tumors
Common side effects with creatine include water retention, dehydration, muscle cramps, weight gain, digestive issues, and kidney stress
Despite the lack of prospective, randomized clinical trials, a few studies have shown carnitine supplementation in patients receiving VPA to result in subjective and objective improvements and to prevent VHT, in parallel with increases in carnitine serum levels
Lyophilization removes water, which is the primary driver of peptide hydrolysis and oxidation
Underwhelming results are sometimes a product-quality issue rather than a protocol issue