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In the ITT population, buntanetap did not meet the primary nor co-primary endpoints in AD patients over placebo
A prominent example of OIS is the H-Ras G12V mutation, which triggers senescence by inducing the DDR mediated by ROS 17
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Characterization of a novel congenic strain of diabetic fatty (WBN/Kob-lepr(fa)) rat
It supplies the mechanistic and directional rationale for the whole compound class, but it is not a human trial and does not establish a human dose
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