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For changes in insulin level, although the result was not statistically significant, the effect size showed that GLP-1 receptor agonists could increase insulin content in vivo, which is consistent with the pharmacological effects of the drug

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Still, observational studies and case reports do show signals that merit careful monitoring in routine care

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GLP-1 therapy for obesity without diabetes

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Four to six months of regular use may show effective results (3)

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