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Tirzepatide and semaglutide are GLP-1 receptor agonists, but Tirzepatides dual agonism offers distinct advantages

Throughout follicular development, intracellular Ca 2+ levels in granulosa cells rise rapidly in response to activation of FSH and LH receptors, oocyte-derived factors, and the pre-ovulatory LH surge [238]

The realistic expectation is hydration improvement visible within 48 hours, surface texture refinement by week 4, fine-line softening from week 8, and cumulative collagen-driven firmness from month 3 onward, sustained through bi-weekly sessions over 4 to 6 months

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This is determined by the thickness of the fat, as generalised obesity may not be appropriate for fat dissolving treatments