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In my practice, only a few patients have reported itchy skin while on GLP-1 medications, says Mir Ali, MD, medical director of MemorialCare Surgical Weight Loss Center at Orange Coast Medical Center in Fountain Valley, CA

Clinical trials comparing supplementation strategies in GLP-1 users remain limited

It's not just about appearance, but also about feeling more active and vibrant every day

These distinctions make both compounds valuable for comparative metabolic and endocrine research studies

Clinical Outcomes of Semaglutide in Patients with MASH The phase 3 ESSENCE trial enrolled 800 patients with biopsy-confirmed MASH and fibrosis stage F2F3 and demonstrated that semaglutide 2.4 mg/week produced significant histological and metabolic benefits over 72 weeks