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CHAC2, downregulated in gastric and colorectal cancers, acted as a tumor suppressor inducing apoptosis and autophagy through unfolded protein response
Additionally, via phosphorylating SLC7A11 at serine 26, mTORC2 reduces the functioning of the SLC7A11 transporter (105)
All in all, balance of redox regulators is essential for health across all life forms, and their pools are consumed or imbalanced as a consequence of diseases
Microarray Hybridization RNA was amplified, labeled, and hybridized onto Single Color SurePrint G3 Mouse GE 8 60K Microarrays (AMADID:046066
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