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However, despite their potential anti-inflammatory benefits, such diets have also been associated with gastrointestinal consequences from increased fermentation of undigested protein and lowered gut microbial diversity 25

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Additionally, the BHBA-activated L-type calcium channel subsequently triggered the activation of Ca 2+ /CaMKII/CREB signaling, and promoted the binding of p-CREB and CBP to Bdnf promoters