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When to split You need a split injection when your calculated volume exceeds 1.00mL (100 units on a U-100 syringe)
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The GLP-1 and GIP components enhance insulin secretion and sensitivity, while the glucagon component, somewhat paradoxically, does not worsen blood sugar control because its glucose-raising effects are offset by the dominant insulin-enhancing effects of the other two pathways
& Matsuzaki, K
The same analysis showed a 59 percent lower risk of new macro-albuminuria (HR 0.41)
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